Eric Dane’s Cause of Death Revealed as ALS-Related Respiratory Failure

March 2, 2026
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The actor died on Thursday, Feb. 19 from respiratory failure related to amyotrophic lateral sclerosis, or ALS

The cause of death of Eric Dane has been confirmed following his death on Thursday, Feb. 19.

The veteran actor died at the age of 53 from respiratory failure related to amyotrophic lateral sclerosis, or ALS, according to People. Dane revealed his ALS diagnosis 10 months ago. The rare degenerative disease affects nerve cells in the brain and spinal cord, as well as breathing. According to the Mayo Clinic, ALS causes loss of muscle control and there is currently no cure for this disease. The exact cause of the disease is still not known, although a small group of cases is inherited.

The National Institute of Neurological Disorders and Stroke states that as motor neurons degenerate and die, they stop sending messages to the muscles, which causes muscle weakness, twitching, and atrophy. Eventually, those with ALS often experience trouble talking, walking, and swallowing, and the symptoms worsen over time. In television appearances and social media posts, Dane often shared the challenges of living with ALS and advocated for awareness and research into the disease.

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“Throughout his journey with ALS, Eric became a passionate advocate for awareness and research, determined to make a difference for others facing the same fight,” Dane’s family shared following his death. “He will be deeply missed, and lovingly remembered always. Eric adored his fans and is forever grateful for the outpouring of love and support he’s received. The family has asked for privacy as they navigate this impossible time.” Dane is survived by his wife and two children.

The actor was mourned by peers, fans, and co-stars alike. His career encompassed memorable performances in Grey’s Anatomy, Euphoria, Burlesque, and more. “He did an incredible job at bringing awareness to this horrible disease in those remaining days, which was really brave of him to do,” Patrick Dempsey said of his Grey’s Anatomy co-star. “It just reminds us that we all have to celebrate every day like it’s our last day.”



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